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Balatskiy V.N., Lisovskiy I.L.

The genetic polymorphism of somatotropin

Cytology and Genetics 1998, v 32, number 2, 92-104


This review deals with the growth hormone genetic polymorphism and presents information about somatotropin variants, which are synthesized in the pituitary gland and in the placenta. The detailed results of somatotropin DNA polymorphism study in different animal species are presented. It is supposed that some DNA alleles which find their source in replacements in non-coding part of the gene, express their phenotype by the deviations in the expression control. The polymorphous somatotropin genetic system may be used as the marker system in the QTL study.




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