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Bolgova L.S.

Nucleolar organizers in the cells of different histological types of lung cancer

Cytology and Genetics 1998, v 32, number 5, 3-9


Nucleolus organizers in the cells of different histologic types and differentiation rate of lung cancer have been first studied on sufficient material obtained when examining 55 patients, operated for lung cancer. It has been established that the most active morphofunctional types of nucleoli--nucleolonemic and compact ones are characteristic of the main histologic forms of lung cancer. The differentiation rate of tumors being decreased, the number of nucleoli and nucleolus organizers is increasing that affects the rate of tension of nucleoproteid metabolism at cytogenetic level.




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