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Pisarchik A.V., Kartel’ N.A., Ermak G.Z., Figge J.
CD44 gene expression in cancerous thyroid cells
Cytology and Genetics 1999, v 33, number 2, 27-32
The peculiarities of alternative CD44 mRNA splicing in thyroid cancer tissue of children from radiocontaminated areas was investigated. CD44 gene expression in thyroid cancer tissues of children exposed to radiation resembled that in spontaneously emerged cancers. It was concluded that CD44 gene expression is not the primary target of radioactive irradiation. Probably, the CD44 mRNA splicing deregulation is the consequence of cancer.
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