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Livshyts' L.A., Yasins'ka O.A.
A Role of Microdeletions of the Chromosome Region Yq11 in the Development of Non-Obstructive Forms of Male Infertility
Cytology and Genetics 2002, v 36, number 5, 73-78
Recent studies have shown that a significant proportion of men with severe infertility had microdeletions of the Y-chromosome. It has thus become important to screen men with a high risk of the Y-chromosome microdeletions, as this will determine if counseling is needed prior to starting infertility treatment. The current state of knowledge about the nature of genes responsible for spermatogenesis and significance of microdeletions of the Y-chromosome for male infertility are analyzed in the review.
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