Tavokina L.V., Baronova E.V., Sopko N.I.

The most frequent chromosomal abnormalities in patients with reproductive problems

TSitologiia i genetika 2007, v 41, Issue 4, 48-55

Results of cytogenetic and molecular-cytogenetic inspection of 210 matrimonial pairs with the problems of reproduction are presented. Different types of chromosomal aberrations have been detected in the karyotypes of the patients in 46 (10,95 %) cases. Such structural chromosomal aberrations as pericentric inversions, Robertsonian translocations, balanced reciprocal translocations, and marker chromosomes as well prevailed the numerical chromosomal aberrations (89,13 and 10,87 % cases accordingly). In the general group of the inspected patients there were 19 cases (4,52 %) characterized by the low level of X and Y chromosome mosaicism. The authors suppose that the patients with the exposed chromosomal abnormalities need the differentiated approach at their treatment.

Tavokina L.V., Baronova E.V., Sopko N.I. The most frequent chromosomal abnormalities in patients with reproductive problems // Tsitol Genet. – 2007. – 41(4). – P. 48-55.