Main page Contacts Preview papers   Contents   Themes Subscription Information to authors Editorial board Standard version

Gene Protective Effect of the Short Chain Derivative of Vitamin E under Alkylic Compound Action

Byshovets T. F., Sajfetdinova G. A., Оchrimenko V. A., Коvalenko V. N., Donchenko G. V.

The gene protective effect of the short chain derivative of vitamin E was investigated in rats intoxicated with embichin and cyclophosphamide. Prophylactic administration of tocopherol derivative for 14 days promotes reduction of the genome and chromosome disturbances in marrow cells caused by this compounds. Correcting influence of tocopherol derivative depends on chemical structure and biologic peculiarities of the alkylating compound.

Tsitologiya i Genetika 2001, vol. 35, no. 1, pp. 10-15

Byshovets T. F., Sajfetdinova G. A., Оchrimenko V. A., Коvalenko V. N., Donchenko G. V. Gene Protective Effect of the Short Chain Derivative of Vitamin E under Alkylic Compound Action, Tsitol Genet., 2001, vol. 35, no. 1, pp. 10-15.