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ESR1 gene allelic polymorphism analysis in population of Ukraine

Livshyts G.B., Kucherenko A.M., Podlesnaja S.S., Kravchenko S.A., Livshits L.A.

SUMMARY. In this study analysis of single nucleotide polymorhisms A351G, С397Т and number of ТА-repeats in ESR1 gene among 199 healthy volunteers from Ukraine was performed. Data concerning genotypes and particular alleles of polymorphic variants distribution were obtained. Possible mechanisms of these polymorphic variants role in ESR1 gene transcription and estrogen receptor expression changes are being discussed.

Key words: estrogen receptor, DNA-polymorphisms, ESR1 gene, population

Tsitologiya i Genetika 2012, vol. 46, no. 4, pp. 31-39

E-mail: livshits imbg.org.ua

Livshyts G.B., Kucherenko A.M., Podlesnaja S.S., Kravchenko S.A., Livshits L.A. ESR1 gene allelic polymorphism analysis in population of Ukraine, Tsitol Genet., 2012, vol. 46, no. 4, pp. 31-39.

In "Cytology and Genetics":
G. B. Livshyts, A. M. Kucherenko, S. S. Podlesna, S. A. Kravchenko, L. A. Livshits Analysis of allelic polymorphism in the ESR1 gene in the Ukraine’s population, Cytol Genet., 2012, vol. 46, no. 4, pp. 220-226
DOI: 10.3103/S009545271204010X