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The molecular biology diagnosis of neoplastic blood diseases
Molecular-biological approaches was applied for detection of Philadelphia chromosome in patients with chronic myeloid and acute lymphoblastic leukemias. It includes bcr-genomic probes and polymerase chain reaction with specific bcr/abl primers. The latter is m c86 ore preferable for clinic use. Different diagnostic methods are compared and leukemias etiology problems are discussed.
Tsitologiya i Genetika 1998, vol. 32, no. 1, pp. 71-78
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