TSitologiya i Genetika 2016, vol. 50, no. 6, 15-22
Cytology and Genetics 2016, vol. 50, no. 6, 366–371, doi: https://www.doi.org/10.3103/S0095452716060098

30 years of the Chernobyl accident. Molecular genetic mechanisms of carcinogenesis of thyroid gland

Tronko N.D., Pushkarev V.M.

SUMMARY. The review presents data on the basic molecular ge-netic mechanisms of formation of papillary thyroid carcinoma. The participation of ionizing radiation in the cancer pathogenesis was analyzed. The role of tu-mor microenvironment, inflammation and nuclear trans-cription factor NF-κB in the initiation and development of papillary thyroid carcinoma was shown.

Keywords: thyroid, papillary carcinoma, oncogenes, ionizing radiation, inflammation, NF-κB
щитоподібна залоза, папілярна карцинома, онкогени, іонізуюча радіація, запалення, NF-κB

TSitologiya i Genetika
2016, vol. 50, no. 6, 15-22

Current Issue
Cytology and Genetics
2016, vol. 50, no. 6, 366–371,
doi: 10.3103/S0095452716060098

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