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30 years of the Chernobyl accident. Molecular genetic mechanisms of carcinogenesis of thyroid gland
SUMMARY. The review presents data on the basic molecular ge-netic mechanisms of formation of papillary thyroid carcinoma. The participation of ionizing radiation in the cancer pathogenesis was analyzed. The role of tu-mor microenvironment, inflammation and nuclear trans-cription factor NF-κB in the initiation and development of papillary thyroid carcinoma was shown.
Key words: thyroid, papillary carcinoma, oncogenes, ionizing radiation, inflammation, NF-κB
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