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Allelic polymorphism C-590T of the gene IL-4 as the most possible genetic marker of high predisposition to development of recurrent episodes of acute obstructive bronchitis in children
SUMMARY. Molecular-genetic study of C-590T polymorphic locus of IL-4 gene in 31 children with recurrent episodes of acute obstructive bronchitis and 50 people who constituted the control population-based group has been carried out. It is proved that the presence of this polymorphic locus leads to three-fold increase of the risk of acute obstructive bronchitis recurrent episodes.
Key words: recurrent episodes of acute obstructive bronchitis, acute respiratory infections, children, molecular genetic analysis, gene polymorphism
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|Coded & Designed by Volodymyr Duplij||Modified 19.08.22|