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Frequency of spontaneous and radiation-induced chromosome aberrations in peripheral blood lymphocytes of persons of different age
SUMMARY. Using the method of GTG staining of human metapha-se chromosomes, the frequency of spontaneous and induced by X-ray in vitro (0,25 Gy) chromosome aberrations as well as the level of chromosomal instability as a result of the bystander effect in the blood lymphocytes of individuals aged from 12 to 102 years had been investigated. The average group frequency of spontaneous chromosome aberrations in adolescents (12–16 years), middle-aged people (33–52 years) and centenarians (90–102 years) was identical (p > 0,05), whereas in elderly persons (60–70 years) it was higher due to increase of chromatid type aberrations rate
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