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General trends in organization and localization of crt-clusters in streptomycetes genomes
SUMMARY. The purpose of the work is to identify the existence of general principles in organization of crt-clusters of streptomycetes and their localization in genomes; to prove similarity in the organization of crt-clusters in phylogenetically related strains. The nucleotide sequences of crt-clusters of 100 strains of streptomycetes were analyzed using BLASTN programs. A number of schemes for organizing crt-clusters in streptomycetes were found. Several main trends in localization and organization of streptomycete crt-clusters were formu-lated. Òhe similarity of crt-cluster organizations in genomes of microorganisms belonging to different strains of same species of streptomycetes was shown. The ability to apply the organization of crp-clusters of Strep-tomyces (as an application to the genetic and phenotypic characteristics that are traditionally used) in the clas-sification of microorganisms within taxa of a lower order (clades, species, subspecies).
Key words: Streptomyces, crt-cluster, genome, scheme of cluster organization, BLASTN analysis
E-mail: LVPolishchuk ukr.net
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