In this study, morphotoxic and cytogenotoxic potency of trade formulation of Propineb were analyzed using Allium cepa assay. The root tips were treated with different concentrations of fungicide Propineb for 24, 48, 72 and 96 h. The effects of propineb on morphological parameters and cytological effects were determined. It was found that Propineb significantly increased the percentage of total abnormality at all concentrations of the Propineb and these increases were dependent on the increasing concentrations for 24, 48 and 72 h. It was determined mitotic chromosomal abnormalities such as irregular metaphase, stickiness, cmitosis, micronucleus, vagrant chromosomes and bridges. These results lead us to the conclusion that Propineb may have genotoxic and cytotoxic properties due to induction in the frequency of total abnormality and a reduction in mitotic index in root tip cells of A. cepa L. It should be necessary to be careful when using pesticides in agricultural areas and should take precautions.
Keywords: Propineb, fungucide, chromosomal aberration, mitotic index
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