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The role of ACE gene I/D polymorphism in development of metabolic disorders in patients with cardiovascular pathology
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The role of angiotensin-converting enzyme (ACE) gene I/D polymorphism in development of cardiovascular pathology (CVP), metabolic syndrom and insulin-independent diabet associated with such metabolic disorders as glucose intolerance and hyperglicemia, intolerance to insulin and hyperinsulinemia, dyslipiproteinemia (DLP) and obesity is discussed. Most of authors consider D-allel and DD genotype to be assosiated with development of DLP and such CVP as ishemic heart disease and myocardial infarction.
Tsitologiya i Genetika 2005, vol. 39, no. 1, pp. 63-70
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